Average Reviews:
(More customer reviews)I use this product for occasional sleeplessness. About 20 minutes after taking it, I get quite sleepy, and can instantly fall asleep. The effect lasts perhaps 2-4 hours. Thus, if you have trouble falling asleep (not staying asleep), this product will help. I found it much more effective than the .3 mg, 3 mg, and 5 mg tablets. Melatonin is a hormone that is produced naturally in our bodies by the pineal gland. It has many functions, but perhaps the main function is to regulate the body wake/sleep cycle, thus, its use as an occassional sleep aid.
Because this is a large dose of Melatonin, it is always best to consult with your MD before using. Melatonin can interact with other body systems and medications. For this reason, I downloaded a precaution sheet from the University of Maryland on melatonin. (see below):
Precautions:
Some people may have vivid dreams or nightmares when they take melatonin. Taking too much melatonin may disrupt circadian rhythms (your "body clock").
Melatonin can cause drowsiness if taken during the day. If you are drowsy the morning after taking melatonin, try taking a lower dose.
Additional side effects include stomach cramps, dizziness, headache, irritability, decreased libido, breast enlargement in men (called gynecomastia), and decreased sperm count.
Pregnant or nursing women should not take melatonin because it could interfere with fertility.
Some studies show that melatonin supplements worsened symptoms of depression. For this reason, people with depression should consult their doctor before using melatonin supplements.
Although many researchers believe that melatonin levels go down with age, newer evidence has brought this theory into question. People older than 65 should ask their doctor before taking melatonin supplements, so blood levels of this hormone can be monitored.
Possible Medication Interactions:
If you are being treated with any of the following medications, you should not use melatonin without first discussing it with your health care provider.
Antidepressant medications -- In an animal study, melatonin supplements reduced the antidepressant effects of desipramine and fluoxetine (Prozac). More research is needed to know if the same thing would happen in people. In addition, fluoxetine (a member of a class of drugs called selective serotonin reuptake inhibitors, or SSRIs) can cause low levels of melatonin in people.
Antipsychotic medications -- A common side effect of antipsychotic medications used to treat schizophrenia is a condition called tardive dyskinesia, which causes involuntary movements. In a study of 22 people with schizophrenia and tardive dyskinesia caused by antipsychotic medications, those who took melatonin supplements had fewer symptoms compared to those who did not take the supplements.
Benzodiazepines -- The combination of melatonin and triazolam (Halcion) improved sleep quality in one study. In addition, a few reports have suggested that melatonin supplements may help people stop using long-term benzodiazepine therapy. (Benzodiazepines are habit-forming.)
Blood pressure medications -- Melatonin may make blood pressure medications like methoxamine (Vasoxyl) and clonidine (Catopres) less effective. In addition, medications in a class called calcium channel blockers may lower melatonin levels. Calcium channel blockers include:
*Nifedipine (Procardia)
*Amlodipine (Norvasc)
*Verapamil (Calan, Isoptin)
*Diltiazem (Cardizem)
*Felodipine (Plendil)
*Nisoldipine (Sular)
*Bepridil (Vascor)
Beta-blockers -- Use of beta-blockers may lower melatonin levels in the body. Beta-blockers include:
*Acebutolol (Sectral)
*Atenolol (Tenormin)
*Bisoprolol (Zebeta)
*Carteolol (Cartrol)
*Metoprolol (Lopressor, Toprol XL)
*Nadolol (Corgard)
*Propranolol (Inderal)
Blood-thinning medications (anticoagulants) -- Melatonin may increase the risk of bleeding from anticoagulant medications such as warfarin (Coumadin).
Interleukin-2 -- In one study of 80 cancer patients, use of melatonin along with interleukin-2 led to more tumor regression and better survival rates than treatment with interleukin-2 alone.
Nonsteroidal anti-inflammatory drugs (NSAIDs) -- NSAIDs such as ibuprofen (Advil, Motrin) may lower levels of melatonin in the blood.
Steroids and immunosuppressant medications -- Melatonin may cause these medication to lose their effectiveness. Do not take melatonin with corticosteroids or other medications used to suppress the immune system.
Tamoxifen -- Preliminary research suggests that the combination of tamoxifen (a chemotherapy drug) and melatonin may benefit some people with breast and other cancers. More research is needed to confirm these results.konedog
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Triple Strength Melatonin 10 Mg 60 Caps
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